INCI: Dimethyl Isosorbide · CAS: 5306-85-4
Dimethyl Isosorbide
Arlasolve DMI is Croda’s branded grade of dimethyl isosorbide, a highly polar, sugar-derived solvent and delivery enhancer used in topical formulations. It improves solubility and stability of challenging actives (e.g., benzoyl peroxide, dihydroxyacetone) and can enhance dermal p
About Dimethyl Isosorbide
Arlasolve DMI is Croda’s branded grade of dimethyl isosorbide, a highly polar, sugar-derived solvent and delivery enhancer used in topical formulations. It improves solubility and stability of challenging actives (e.g., benzoyl peroxide, dihydroxyacetone) and can enhance dermal penetration to boost efficacy while helping reduce irritation potential. The clear, low-odor liquid is biodegradable and compatible with water and many organic phases, aiding in the formation of clear solutions and stable systems. It is widely used in acne care, anti-aging, brightening, and self-tanning products.
Function: solvent, penetration enhancer, delivery system, stabilizer for actives
Recommended Usage
Skin care: 1–10% typical; up to ~15% for difficult-to-solubilize actives. Start at 2–5% to enhance active delivery and reduce irritation.
Hair care: 0.5–5% typical as solvent/vehicle for actives and fragrance; adjust based on actives loading and clarity targets.
Regulatory Status
- EU (max No specific maximum; use per safety assessment.): Not specifically restricted in Regulation (EC) No 1223/2009 Annexes; use according to general safety and impurity limits.
- US (max No specific maximum; formulate to intended safe use.): No specific FDA cosmetic use restriction; use per general safety requirements (21 CFR for cosmetics).
- ASEAN (max No specific maximum; follow product safety assessment.): Not listed in Annex II (prohibited) or Annex III (restricted) of the ASEAN Cosmetic Directive; subject to general safety.
Suppliers & Distributors
- Croda International Plc (Manufacturer)
- SpecialChem (directory listing) (Distributor)
- CM Studio+ (listing) (Distributor)
Common questions about Dimethyl Isosorbide
What is Dimethyl Isosorbide?
Arlasolve DMI is Croda’s branded grade of dimethyl isosorbide, a highly polar, sugar-derived solvent and delivery enhancer used in topical formulations. It improves solubility and stability of challenging actives (e.g., benzoyl peroxide, dihydroxyacetone) and can enhance dermal p
What is the INCI name for Dimethyl Isosorbide?
The INCI name for Dimethyl Isosorbide is Dimethyl Isosorbide. INCI (International Nomenclature of Cosmetic Ingredients) is the standardized naming system used on cosmetic product labels worldwide.
What is the CAS number for Dimethyl Isosorbide?
The CAS number for Dimethyl Isosorbide (Dimethyl Isosorbide) is 5306-85-4. The CAS number is the unique chemical identifier assigned by the Chemical Abstracts Service.
What does Dimethyl Isosorbide do in cosmetic formulations?
In cosmetic formulations, Dimethyl Isosorbide (Dimethyl Isosorbide) functions as: solvent, penetration enhancer, delivery system, stabilizer for actives.
What percentage of Dimethyl Isosorbide is typically used in cosmetics?
Typical use levels for Dimethyl Isosorbide (Dimethyl Isosorbide) in cosmetic formulations: In skin care: 1–10% typical; up to ~15% for difficult-to-solubilize actives. Start at 2–5% to enhance active delivery and reduce irritation.. In hair care: 0.5–5% typical as solvent/vehicle for actives and fragrance; adjust based on actives loading and clarity targets.. Always confirm against the supplier's technical data sheet and the regulatory limits for your target market.
Is Dimethyl Isosorbide allowed in cosmetics in major markets?
Dimethyl Isosorbide (Dimethyl Isosorbide) is regulated as follows in major markets: EU (max No specific maximum; use per safety assessment.); US (max No specific maximum; formulate to intended safe use.); ASEAN (max No specific maximum; follow product safety assessment.). See the Regulatory Status section above for the specific restrictions and conditions in each territory.
Who manufactures Dimethyl Isosorbide?
Dimethyl Isosorbide (Dimethyl Isosorbide) is manufactured by suppliers including Croda International Plc. Sign in to Chemdex to see full contact details, SDS / TDS documents, and regional offices for every supplier.