INCI: Acetyl Hexapeptide-8 · CAS: 616204-22-9
Argireline
A peptide marketed as a topical 'Botox-like' wrinkle relaxer.
About Argireline
Acetyl Hexapeptide-8, also known by the trade name Argireline®, is a synthetic peptide that helps reduce the appearance of fine lines and wrinkles. It works by inhibiting the SNARE complex and the release of neurotransmitters, thus limiting facial muscle contractions. Often marketed as a safe alternative to botulinum toxin, it is widely used in anti-aging skincare formulations.
Function: anti-aging, wrinkle-reduction, skin-restoration
Recommended Usage
Skin care: 0.05% to 5%, commonly used at around 2% in serums and creams for anti-aging benefits.
Hair care: Not widely used in haircare; potential application as an anti-aging scalp treatment.
Regulatory Status
- EU (max No specific limits; adhere to Good Manufacturing Practices.): Permitted for cosmetic use; ensure safety assessment compliance.
- US (max No specific limits; formulation must meet regulations for safety and efficacy.): Permitted for cosmetic use under FDA regulations.
- ASEAN (max No specific limits; subject to individual country mandates.): Allowed for inclusion in cosmetic formulations.
Suppliers & Distributors
- Lipotec (Lubrizol Company) (Manufacturer)
- Sederma (Croda International Group) (Manufacturer)
- Active Peptide Company (Manufacturer)
- Lotioncrafter (Distributor)
- Spectrum Chemical (Distributor)
- HBNO® (Distributor)
Common questions about Argireline
What is Argireline?
A peptide marketed as a topical 'Botox-like' wrinkle relaxer.
What is the INCI name for Argireline?
The INCI name for Argireline is Acetyl Hexapeptide-8. INCI (International Nomenclature of Cosmetic Ingredients) is the standardized naming system used on cosmetic product labels worldwide.
What is the CAS number for Argireline?
The CAS number for Argireline (Acetyl Hexapeptide-8) is 616204-22-9. The CAS number is the unique chemical identifier assigned by the Chemical Abstracts Service.
What does Argireline do in cosmetic formulations?
In cosmetic formulations, Argireline (Acetyl Hexapeptide-8) functions as: anti-aging, wrinkle-reduction, skin-restoration.
What percentage of Argireline is typically used in cosmetics?
Typical use levels for Argireline (Acetyl Hexapeptide-8) in cosmetic formulations: In skin care: 0.05% to 5%, commonly used at around 2% in serums and creams for anti-aging benefits.. In hair care: Not widely used in haircare; potential application as an anti-aging scalp treatment.. Always confirm against the supplier's technical data sheet and the regulatory limits for your target market.
Is Argireline allowed in cosmetics in major markets?
Argireline (Acetyl Hexapeptide-8) is regulated as follows in major markets: EU (max No specific limits; adhere to Good Manufacturing Practices.); US (max No specific limits; formulation must meet regulations for safety and efficacy.); ASEAN (max No specific limits; subject to individual country mandates.). See the Regulatory Status section above for the specific restrictions and conditions in each territory.
Who manufactures Argireline?
Argireline (Acetyl Hexapeptide-8) is manufactured by suppliers including Lipotec (Lubrizol Company), Sederma (Croda International Group), Active Peptide Company. Sign in to Chemdex to see full contact details, SDS / TDS documents, and regional offices for every supplier.